Gestational diabetes is associated with postpartum hemorrhage in Indigenous Australian women in the PANDORA study: A prospective cohort

IM Lucas; ELM Barr; F Barzi; DK Longmore; IL Lee; M Kirkwood; C Whitbread; C Connors; JA Boyle; D Simon; A Goodrem; ADH Brown; J Oats; HD McIntyre; JE Shaw; L Maple-Brown

Journal article

Gestational diabetes is associated with postpartum hemorrhage in Indigenous Australian women in the PANDORA study: A prospective cohort

IM Lucas, ELM Barr, F Barzi, DK Longmore, IL Lee, M Kirkwood, C Whitbread, C Connors, JA Boyle, D Simon, A Goodrem, ADH Brown, J Oats, HD McIntyre, JE Shaw, L Maple-Brown

International Journal of Gynecology and Obstetrics | WILEY | Published : 2021

DOI: 10.1002/ijgo.13846

Abstract

Objective: To assess associations of hyperglycemia in pregnancy with the risk of postpartum hemorrhage (PPH) in a prospective cohort of Indigenous and non-Indigenous women, compared with normoglycemia. Methods: Data were from 1102 (48% Indigenous) women of the Pregnancy And Neonatal Diabetes Outcomes in Remote Australia (PANDORA) Study. Age-adjusted associations of gestational diabetes mellitus (GDM) or pre-existing type 2 diabetes mellitus (T2DM), obstetric and demographic covariables with PPH (blood loss ≥500 ml) were assessed using logistic regression. Multivariable-adjusted models included Indigenous ethnicity, diabetes type and their interaction. Results: A higher proportion of Indigeno..

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University of Melbourne Researchers

Danielle Longmore Author

I-Lynn Lee Author

Related Projects (2)

PREGNANCY AND NEONATAL DIABETES OUTCOMES IN REMOTE AUSTRALIA (PANDORA) COHORT

The PANDORA study is a longitudinal birth cohort study recruited from a clinical register of Northern Territory women with diabetes in pregn..

NTDIP: NORTHERN TERRITORY DIABETES IN PREGNANCY PROJECT

Diabetes in pregnancy provides exposure to high sugar levels before birth which can result in the child developing obesity, diabetes and car..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council of Australia (NHMRC Partnership Project Grant #1032116, NHMRC #1078333). The funder played no role in conducting the research or writing the paper. IML was not funded for this study; ELMB was supported by a National Heart Foundation post--doctoral fellowship (#101291); ILL was supported by an Australian Postgraduate Award and Menzies scholarship; JAB was supported by NHMRC Career Development Fellowship; AB was supported by a Sylvia and Charles Viertel Senior Medical Research Fellowship and an NHMRC Senior Research Fellowship #1137563; JES was supported by NHMRC Investigator Grant #1173952; LMB was supported by NHMRC Practitioner Fellowship #1078477 and NHMRC Investigator Grant #1194698. The views expressed in this paper are those of the authors and do not reflect the views of the NHMRC.